If a patient has known exposure to lead (they worked in a welding shop or smoked heavily) or was found high by mineral analysis (see section on trace mineral testing) then we pursue treatment with a series of chelation treatments. In the initial testing we do a provocative test which means giving the patient a chelating agent and having the patient collect their urine for 24 hours. Â We send that urine to the lab for heavy metal analysis. Â We usually check progress by doing a Provocative Test every fifth treatment and when the levels are down and the symptoms subside, we discontinue active treatment and check a provocative test every 6 to 12 months to make sure the patient was fully detoxified. The choice of chelating agent depends upon what toxic metal we are after. EDTA is good for Lead and Cadmium. One problem is that EDTA does not cross the blood brain barrier and other chelators may need to be used such as DMPS. Aluminum and iron are removed with another chelator, desferroxamine, which we use in Hemochromatosis. If you choose to pursue this therapy, the Doctor will explain what is best for your specific conditions.